Accession | ARO:3003846 |
Definition | ADC beta-lactamases, also known as AmpC beta-lactamases, are cephalosporinases with extended-spectrum resistance to cephalosporins but not to carbapenems. ADC beta-lactamases are found in Acinetobacter sp. and Oligella urethralis. |
Drug Class | cephalosporin |
Resistance Mechanism | antibiotic inactivation |
Classification | 12 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + determinant of antibiotic resistance + antibiotic inactivation [Resistance Mechanism] + antibiotic molecule + antibiotic inactivation enzyme + beta-lactam antibiotic + determinant of beta-lactam resistance + hydrolysis of antibiotic conferring resistance + cephem + hydrolysis of beta-lactam antibiotic by serine beta-lactamase + beta-lactamase |
Parent Term(s) | 2 ontology terms | Show |
Sub-Term(s) | 47 ontology terms | Show + ADC-11 + ADC-1 + ADC-2 + ADC-3 + ADC-4 + ADC-5 + ADC-6 + ADC-7 + ADC-8 + ADC-12 + ADC-13 + ADC-14 + ADC-15 + ADC-16 + ADC-17 + ADC-18 + ADC-19 + ADC-20 + ADC-21 + ADC-22 + ADC-23 + ADC-25 + ADC-31 + ADC-39 + ADC-41 + ADC-42 + ADC-43 + ADC-44 + ADC-56 + ADC-61 + ADC-74 + ADC-75 + ADC-76 + ADC-77 + ADC-78 + ADC-79 + ADC-80 + ADC-81 + ADC-82 + ADC-10 + ADC-30 + ADC-59 + ADC-62 + ADC-73 + ADC-60 + ADC-67 + ADC-58 |
Publications | Hujer KM, et al. 2005. Antimicrob Agents Chemother 49(7): 2941-2948. Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes. (PMID 15980372) |