ADC beta-lactamase without carbapenemase activity [AMR Gene Family]

Accession ARO:3003846
DefinitionADC beta-lactamases, also known as AmpC beta-lactamases, are cephalosporinases with extended-spectrum resistance to cephalosporins but not to carbapenems. ADC beta-lactamases are found in Acinetobacter sp. and Oligella urethralis.
Drug Classcephalosporin
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ class C beta-lactamase
Sub-Term(s)
47 ontology terms | Show
Publications

Hujer KM, et al. 2005. Antimicrob Agents Chemother 49(7): 2941-2948. Identification of a new allelic variant of the Acinetobacter baumannii cephalosporinase, ADC-7 beta-lactamase: defining a unique family of class C enzymes. (PMID 15980372)