quinupristin-dalfopristin [Antibiotic]

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Accession ARO:3004022
Synonym(s)Synercid
DefinitionAn antibiotic cocktail of the streptogramin A dalfopristin and the streptogramin B quinupristin antibiotics. Used particularly to treat MRSA and vancomycin-resistant Enterococcus.
SMILESCCN(CC)CCS(=O)(=O)[C@@H]1CCN2C(=O)c3coc(n3)CC(=O)C[C@H](O)/C=C(C)/C=C/CNC(=O)/C=C/[C@@H](C)[C@@H](C(C)C)OC(=O)[C@@H]12.CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2CC(=O)[C@H](CS[C@@H]3CN4CCC3CC4)CN2C(=O)[C@H](Cc2ccc(N(C)C)cc2)N(C)C(=O)[C@@H]2CCCN2C1=O
PubChem25199981
ChEMBLCHEMBL3137691
ChEBI8733
Drug Classstreptogramin antibiotic, streptogramin B antibiotic, streptogramin A antibiotic
Classification5 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ has_part quinupristin [Antibiotic]
+ has_part dalfopristin [Antibiotic]
+ antibiotic mixture
Sub-Term(s)
1 ontology terms | Show
+ clcD confers_resistance_to_antibiotic
Curator Acknowledgements
Curator Description Most Recent Edit