tetAB(46)

Accession ARO:3004031
DefinitiontetAB(46) is a heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity. Both tetA(46) and tetB(46) genes are required for resistance.
AMR Gene FamilyATP-binding cassette (ABC) antibiotic efflux pump
Drug Classpleuromutilin antibiotic, macrolide antibiotic, cephalosporin, rifamycin antibiotic, acridine dye, penam, peptide antibiotic, tetracycline antibiotic, fluoroquinolone antibiotic, nitroimidazole antibiotic
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification18 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_antibiotic tetracycline [Antibiotic]
+ ATP-binding cassette (ABC) antibiotic efflux pump [AMR Gene Family]
Sub-Term(s)
2 ontology terms | Show
+ tetA(46) part_of
+ tetB(46) part_of
Publications

Warburton PJ, et al. 2013. J. Antimicrob. Chemother. 68(1):17-22 TetAB46, a predicted heterodimeric ABC transporter conferring tetracycline resistance in Streptococcus australis isolated from the oral cavity. (PMID 22941900)