ATP-binding cassette (ABC) antibiotic efflux pump [AMR Gene Family]

Accession ARO:0010001
Synonym(s)ABC type drug efflux
DefinitionDirected pumping of antibiotic out of a cell to confer resistance. ATP-binding cassette (ABC) transporters are present in all cells of all organisms and use the energy of ATP binding/hydrolysis to transport substrates across cell membranes.
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
25 ontology terms | Show

Fath MJ and Kolter R. 1993. Microbiol Rev 57(4): 995-1017. ABC transporters: bacterial exporters. (PMID 8302219)