Candida spp. CDR2

Accession ARO:3007554
DefinitionCDR2 is a Pleiotropic drug resistance gene encoding ABC transporters that contributes to multidrug antifungal resistance in Candida spp.
AMR Gene FamilyATP-binding cassette (ABC) antibiotic efflux pump
Drug Classallylamine antibiotic, triazole antibiotic
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification9 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ confers_resistance_to_antibiotic fluconazole [Antibiotic]
+ confers_resistance_to_antibiotic terbinafine [Antibiotic]
+ ATP-binding cassette (ABC) antibiotic efflux pump [AMR Gene Family]
2 ontology terms | Show

Sanglard D, et al. 1997. Microbiology (Reading) 143 ( Pt 2):405-416 Cloning of Candida albicans genes conferring resistance to azole antifungal agents: characterization of CDR2, a new multidrug ABC transporter gene. (PMID 9043118)

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