tetracycline antibiotic [Drug Class]

Accession ARO:3000050
DefinitionThese antibiotics are derived from tetracycline, a polyketide antibiotic that inhibits the 30S subunit of bacterial ribosomes.
Classification1 ontology terms | Show
Parent Term(s)1 ontology terms | Show
16 ontology terms | Show
+ doxycycline [Antibiotic]
+ glycylcycline [Drug Class]
+ minocycline [Antibiotic]
+ chlortetracycline [Antibiotic]
+ demeclocycline [Antibiotic]
+ oxytetracycline [Antibiotic]
+ Omadacycline [Antibiotic]
+ Eravacycline [Antibiotic]
+ tetracycline [Antibiotic]
+ Sarecycline [Antibiotic]
+ antibiotic sensitive 16S rRNA targeted_by
+ tetracycline-resistant ribosomal protection protein [AMR Gene Family] confers_resistance_to_drug_class
+ 16S rRNA with mutation conferring resistance to tetracycline derivatives [AMR Gene Family] confers_resistance_to_drug_class
+ lmrP confers_resistance_to_drug_class
+ tetracycline inactivation enzyme [AMR Gene Family] confers_resistance_to_drug_class
+ Sugar Porin (SP) [AMR Gene Family] confers_resistance_to_drug_class

Chopra I and Roberts M. 2001. Microbiol Mol Biol Rev 65(2): 232-260. Tetracycline antibiotics: mode of action, applications, molecular biology, and epidemiology of bacterial resistance. (PMID 11381101)