Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:0000002 |
Definition | A family of proteins known to bind to the 30S ribosomal subunit. This interaction prevents tetracycline and tetracycline derivatives from inhibiting ribosomal function. Thus, these proteins confer elevated resistance to tetracycline derivatives as a ribosomal protection protein. |
Drug Class | tetracycline antibiotic |
Resistance Mechanism | antibiotic target protection |
Classification | 5 ontology terms | Show |
Parent Term(s) | 2 ontology terms | Show + confers_resistance_to_drug_class tetracycline antibiotic [Drug Class] + antibiotic target protection protein |
Sub-Term(s) | 21 ontology terms | Show + tet(32) + tetB(P) + tet(W) + tet(T) + tet(S) + tet(Q) + tet(O) + tet(M) + tet(44) + Streptomyces rimosus otr(A) + rpsJ + tet(36) + tet(W/N/W) + tet(61) + tet(O/32/O) + tet(O/M/O) + tet(O/W) + tet(O/W/32/O) + tet(O/W/O) + tet(W/32/O) + Streptomyces lividans otr(A) |
Curator | Description | Most Recent Edit |
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