demeclocycline [Antibiotic]

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Accession ARO:3000667
Synonym(s)declomycin DMCTC
DefinitionDemeclocycline is a tetracycline analog with 7-chloro and 6-methyl groups. Due to its fast absorption and slow excretion, it maintains higher effective blood levels compared to other tetracyclines.
Drug Classtetracycline antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
13 ontology terms | Show
+ antibiotic sensitive 16S rRNA targeted_by_antibiotic
+ tet(X) confers_resistance_to_antibiotic
+ tet(32) confers_resistance_to_antibiotic
+ tet(36) confers_resistance_to_antibiotic
+ tetB(P) confers_resistance_to_antibiotic
+ tet(Q) confers_resistance_to_antibiotic
+ tet(S) confers_resistance_to_antibiotic
+ tet(T) confers_resistance_to_antibiotic
+ tet(W) confers_resistance_to_antibiotic
+ tet(M) confers_resistance_to_antibiotic
+ tet(O) confers_resistance_to_antibiotic
+ tet(44) confers_resistance_to_antibiotic
+ lmrP confers_resistance_to_antibiotic

De Troyer A. 1977. JAMA 237(25): 2723-2726. Demeclocycline. Treatment for syndrome of inappropriate antidiuretic hormone secretion. (PMID 194065)