DIM beta-lactamase [AMR Gene Family]

Accession ARO:3004208
DefinitionDIM type beta-lactamases were first identified from a carbapenem-resistant Pseudomonas stutzeri strain isolated from a Dutch patient. Encoded in mobile elements, these MBLs significantly hydrolyze broad-spectrum cephalosporins and carbapenems.
Drug Classcephalosporin, carbapenem
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ subclass B1 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
1 ontology terms | Show

Poirel L, et al. 2010. Antimicrob Agents Chemother 54(6): 2420-2424. Characterization of DIM-1, an integron-encoded metallo-beta-lactamase from a Pseudomonas stutzeri clinical isolate in the Netherlands. (PMID 20308383)