HMB beta-lactamase [AMR Gene Family]

Accession ARO:3004209
DefinitionFirst identified from a multi-drug resistant Pseudomonas aeruginosa clinical isolate in 2012, HMB type beta-lactamases can be encoded in transposons and hydrolyze carbapenems.
Drug Classcarbapenem
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ subclass B1 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class carbapenem [Drug Class]
1 ontology terms | Show

Pfennigwerth N, et al. 2017. J. Antimicrob. Chemother. 72(4):1068-1073 Genetic and biochemical characterization of HMB-1, a novel subclass B1 metallo-β-lactamase found in a Pseudomonas aeruginosa clinical isolate. (PMID 28065891)