AIM beta-lactamase [AMR Gene Family]

Accession ARO:3004216
DefinitionA subclass B3 family of beta-lactamases that confer resistance to a range of beta-lactam antibiotics including penams, cephamycins, and cephalosporins.
Drug Classpenam, cephalosporin, cephamycin
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ subclass B3 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class penam [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class cephamycin [Drug Class]
1 ontology terms | Show

Leiros HK, et al. 2012. Antimicrob. Agents Chemother. 56(8):4341-53 Crystal structure of the mobile metallo-β-lactamase AIM-1 from Pseudomonas aeruginosa: insights into antibiotic binding and the role of Gln157. (PMID 22664968)