cefotaxime-ceftiofur-tazobactam-clavulanate [Antibiotic+Adjuvant]

Accession ARO:3007040
DefinitionA combination therapy for multidrug resistant pathogens consisting of two cephalosporin antibiotics (cefotaxime and ceftiofur) with two beta-lactamase inhibitors (tazobactam and clavulanate) encapsulated in a nanoparticle. They were shown to have efficient antimicrobial activity against multidrug resistant extended-spectrum beta-lactamase producing Enterobacteriaceae.
Drug Classcephalosporin
Classification10 ontology terms | Show
Parent Term(s)5 ontology terms | Show
+ antibiotic mixture
+ has_part clavulanic acid [Adjuvant]
+ has_part tazobactam [Adjuvant]
+ has_part ceftiofur [Antibiotic]
+ has_part cefotaxime [Antibiotic]

Fan P, et al. 2022. Int J Biol Macromol 195:506-514 A novel combination therapy for multidrug resistant pathogens using chitosan nanoparticles loaded with β-lactam antibiotics and β-lactamase inhibitors. (PMID 34920071)