cefotaxime [Antibiotic]

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Accession ARO:3000645
Synonym(s)cefotaxime acid CTX
DefinitionCefotaxime is a semisynthetic cephalosporin taken parenterally. It is resistant to most beta-lactamases and active against Gram-negative rods and cocci due to its aminothiazoyl and methoximino functional groups.
Drug Classcephalosporin
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ cephalosporin [Drug Class]
Sub-Term(s)
9 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ CmeABC confers_resistance_to_antibiotic
+ CAM-1 confers_resistance_to_antibiotic
+ abcA confers_resistance_to_antibiotic
+ Serratia marcescens Omp1 confers_resistance_to_antibiotic
+ Klebsiella pneumoniae OmpK37 confers_resistance_to_antibiotic
+ ACI-1 confers_resistance_to_antibiotic
+ cefotaxime-clavulanic acid has_part
+ cefotaxime-tazobactam has_part
Publications

Todd PA and Brogden RN. 1990. Drugs 40(4): 608-651. Cefotaxime. An update of its pharmacology and therapeutic use. (PMID 2083516)