clavulanic acid [Adjuvant]

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Accession ARO:0000079
Synonym(s)Clavulansaeure acidum clavulanicum clavulanate Acido clavulanico Sodium Clavulanate Acide clavulanique Isoclavulanic acid Clavulox
DefinitionClavulanic acid is a beta-lactamase inhibitor (marketed by GlaxoSmithKline, formerly Beecham) combined with penicillin group antibiotics to overcome certain types of antibiotic resistance. It is used to overcome resistance in bacteria that secrete beta-lactamase, which otherwise inactivates most penicillins.
Classification4 ontology terms | Show
Parent Term(s)20 ontology terms | Show
+ beta-lactam derived beta-lactamase inhibitor
+ is_small_molecule_inhibitor TEM-1
+ is_small_molecule_inhibitor TEM-2
+ is_small_molecule_inhibitor TEM-3
+ is_small_molecule_inhibitor TEM-5
+ is_small_molecule_inhibitor TEM-6
+ is_small_molecule_inhibitor TEM-7
+ is_small_molecule_inhibitor TEM-9
+ is_small_molecule_inhibitor TEM-10
+ is_small_molecule_inhibitor TEM-26
+ is_small_molecule_inhibitor TEM-12
+ is_small_molecule_inhibitor SHV-1
+ is_small_molecule_inhibitor SHV-2
+ is_small_molecule_inhibitor SHV-3
+ is_small_molecule_inhibitor SHV-5
+ is_small_molecule_inhibitor CTX-M-1
+ is_small_molecule_inhibitor CTX-M-8
+ is_small_molecule_inhibitor CTX-M-15
+ is_small_molecule_inhibitor CTX-M-14
+ is_small_molecule_inhibitor CTX-M-16
7 ontology terms | Show
+ amoxicillin-clavulanic acid [Antibiotic+Adjuvant] has_part
+ ticarcillin-clavulanic acid [Antibiotic+Adjuvant] has_part
+ ceftazidime-clavulanic acid [Antibiotic+Adjuvant] has_part
+ cefoxitin-clavulanate [Antibiotic+Adjuvant] has_part
+ cefotaxime-clavulanic acid [Antibiotic+Adjuvant] has_part
+ aztreonam-clavulanate [Antibiotic+Adjuvant] has_part
+ cefotaxime-ceftiofur-tazobactam-clavulanate [Antibiotic+Adjuvant] has_part