AAC(3)-IV

Accession ARO:3007387
DefinitionA family of aminoglycoside 3-N-acetyltransferase enzymes which inactivate gentamicin, tobramycin and apramycin through enzymatic acetylation, thereby conferring resistance to these compounds.
AMR Gene FamilyAAC(3)
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification10 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ AAC(3) [AMR Gene Family]
Sub-Term(s)
2 ontology terms | Show
Publications

Shaw KJ, et al. 1993. Microbiol Rev 57(1): 138-163. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. (PMID 8385262)