caspofungin [Antibiotic]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3007501
DefinitionCaspofungin is an antibiotic, particularly antifungal, derived from echinocandins. It has a wide range of activity against fungi and yeasts.
SMILESCC[C@H](C)C[C@H](C)CCCCCCCCC(=O)N[C@H]1C[C@@H](O)[C@@H](NCCN)NC(=O)[C@@H]2[C@@H](O)CCN2C(=O)[C@H]([C@H](O)CCN)NC(=O)[C@H]([C@H](O)[C@@H](O)c2ccc(O)cc2)NC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@H]([C@@H](C)O)NC1=O
PubChem3035406
ChEBI474180
ChEMBLCHEMBL1630575
Drug Classechinocandin antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
2 ontology terms | Show
+ Candida spp. High Osmolarity Glycerol 1 conferring resistance to caspofungin via absence confers_resistance_to_antibiotic
+ antifungal resistance-associated MSH2 [AMR Gene Family] confers_resistance_to_antibiotic
Publications

Keating GM, et al. 2001. Drugs 61(8):1121-9; discussion 1130-1 Caspofungin. (PMID 11465873)

Curator Acknowledgements
Curator Description Most Recent Edit