ACC beta-lactamase [AMR Gene Family]

Accession ARO:3000073
DefinitionACC beta-lactamases or Ambler class C beta-lactamases are AmpC beta-lactamases. They possess an interesting resistance phenotype due to their low activity against cephamycins.
Drug Classmonobactam, cephalosporin, penam
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ confers_resistance_to_drug_class monobactam [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class penam [Drug Class]
+ class C beta-lactamase
Sub-Term(s)
5 ontology terms | Show
Publications

Bauernfeind A, et al. 1999. Antimicrob Agents Chemother 43(8): 1924-1931. A novel type of AmpC beta-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia. (PMID 10428914)