Accession | ARO:3000073 |
Definition | ACC beta-lactamases or Ambler class C beta-lactamases are AmpC beta-lactamases. They possess an interesting resistance phenotype due to their low activity against cephamycins. |
Drug Class | monobactam, cephalosporin, penicillin beta-lactam |
Resistance Mechanism | antibiotic inactivation |
Classification | 10 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + determinant of antibiotic resistance + antibiotic inactivation [Resistance Mechanism] + antibiotic inactivation enzyme + hydrolysis of antibiotic conferring resistance + antibiotic molecule + hydrolysis of beta-lactam antibiotic by serine beta-lactamase + beta-lactam antibiotic + beta-lactamase |
Parent Term(s) | 4 ontology terms | Show + confers_resistance_to_drug_class monobactam [Drug Class] + confers_resistance_to_drug_class cephalosporin [Drug Class] + confers_resistance_to_drug_class penicillin beta-lactam [Drug Class] + class C beta-lactamase |
Sub-Term(s) | 7 ontology terms | Show |
Publications | Bauernfeind A, et al. 1999. Antimicrob Agents Chemother 43(8): 1924-1931. A novel type of AmpC beta-lactamase, ACC-1, produced by a Klebsiella pneumoniae strain causing nosocomial pneumonia. (PMID 10428914) |
Curator | Description | Most Recent Edit |
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