sigma factor conferring resistance to rifampin

Accession ARO:3000261
DefinitionWhen bound to different sigma factors, RNA-polymerase may possess an altered sensitivity to rifampin-mediated inhibition.
Drug Classrifamycin antibiotic
Resistance Mechanismantibiotic target protection
Classification7 ontology terms | Show
Parent Term(s)5 ontology terms | Show
+ rifampin-resistant RNA polymerase-binding protein
+ confers_resistance_to_antibiotic rifabutin [Antibiotic]
+ confers_resistance_to_antibiotic rifampin [Antibiotic]
+ confers_resistance_to_antibiotic rifapentine [Antibiotic]
+ confers_resistance_to_antibiotic rifaximin [Antibiotic]

Wegrzyn A, et al. 1998. FEBS Lett 440(1-2): 172-174. Differential inhibition of transcription from sigma70- and sigma32-dependent promoters by rifampicin. (PMID 9862449)