rifaximin [Antibiotic]

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Accession ARO:3000517
DefinitionRifaximin is a semi-synthetic rifamycin used to treat traveller's diarrhea. Rifaximin inhibits RNA synthesis by binding to the beta subunit of bacterial RNA polymerase.
Drug Classrifamycin antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ rifamycin antibiotic [Drug Class]
Sub-Term(s)
14 ontology terms | Show
+ rifampin ADP-ribosyltransferase (Arr) [AMR Gene Family] confers_resistance_to_antibiotic
+ DnaA confers_resistance_to_antibiotic
+ RbpA confers_resistance_to_antibiotic
+ rpoB2 confers_resistance_to_antibiotic
+ sigma factor conferring resistance to rifampin confers_resistance_to_antibiotic
+ Escherichia coli rpoB mutants conferring resistance to rifampicin confers_resistance_to_antibiotic
+ Mycobacterium leprae rpoB mutations conferring resistance to rifampicin confers_resistance_to_antibiotic
+ Mycobacterium tuberculosis rpoB mutants conferring resistance to rifampicin confers_resistance_to_antibiotic
+ Staphylococcus aureus rpoB mutants conferring resistance to rifampicin confers_resistance_to_antibiotic
+ rgt1438 confers_resistance_to_antibiotic
+ iri confers_resistance_to_antibiotic
+ rphB confers_resistance_to_antibiotic
+ rphA confers_resistance_to_antibiotic
+ rifamycin sensitive beta-subunit of RNA polymerase (rpoB) targeted_by_antibiotic
Publications

Huang DB and DuPont HL. 2005. J Infect 50(2): 97-106. Rifaximin--a novel antimicrobial for enteric infections. (PMID 15667909)