rifamycin sensitive beta-subunit of RNA polymerase (rpoB)

Accession ARO:3000737
DefinitionThe beta-subunit of RNA polymerase is targeted as a complex. When blocked, RNA strand elongation cannot continue after the first few nucleotides.
Drug Classrifamycin antibiotic
Classification3 ontology terms | Show
Parent Term(s)6 ontology terms | Show
+ targeted_by rifamycin antibiotic [Drug Class]
+ targeted_by_antibiotic rifabutin [Antibiotic]
+ targeted_by_antibiotic rifampin [Antibiotic]
+ targeted_by_antibiotic rifapentine [Antibiotic]
+ targeted_by_antibiotic rifaximin [Antibiotic]
+ antibiotic sensitive beta-subunit of RNA polymerase (rpoB)
1 ontology terms | Show

Floss HG and Yu TW. 2005. Chem Rev 105(2): 621-632. Rifamycin-mode of action, resistance, and biosynthesis. (PMID 15700959)