Accession | ARO:3000889 |
Definition | TEM-18 is an extended-spectrum beta-lactamase that has been found in clinical isolates. |
AMR Gene Family | TEM beta-lactamase |
Drug Class | penam, monobactam, penem, cephalosporin |
Resistance Mechanism | antibiotic inactivation |
Classification | 17 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + antibiotic inactivation [Resistance Mechanism] + antibiotic molecule + determinant of antibiotic resistance + antibiotic inactivation enzyme + hydrolysis of antibiotic conferring resistance + beta-lactam antibiotic + cephem + penam [Drug Class] + beta-lactamase + hydrolysis of beta-lactam antibiotic by serine beta-lactamase + ampicillin [Antibiotic] + monobactam [Drug Class] + penem [Drug Class] + class A beta-lactamase + cephalosporin [Drug Class] |
Parent Term(s) | 1 ontology terms | Show + TEM beta-lactamase [AMR Gene Family] |
Publications | Chanal CM, et al. 1989. Antimicrob Agents Chemother 33(11): 1915-1920. Multiplicity of TEM-derived beta-lactamases from Klebsiella pneumoniae strains isolated at the same hospital and relationships between the responsible plasmids. (PMID 2558614) |