pleuromutilin [Antibiotic]

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Accession ARO:3001317
DefinitionPleuromutilin is a natural product antibiotic produced by Clitopilus passeckerianus. Related antibiotics of clinical significance, such as tiamulin and retapamulin, are semi-synthetic derivatives of this compound.
Drug Classpleuromutilin antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
8 ontology terms | Show
+ eatAv confers_resistance_to_antibiotic
+ lsaC confers_resistance_to_antibiotic
+ lsaA confers_resistance_to_antibiotic
+ lsaB confers_resistance_to_antibiotic
+ lsaE confers_resistance_to_antibiotic
+ TaeA confers_resistance_to_antibiotic
+ Mycoplasma gallisepticum 23S rRNA mutation conferring resistance to pleuromutilin antibiotics confers_resistance_to_antibiotic
+ tva(A) confers_resistance_to_antibiotic

Fazakerley NJ, et al. 2013. Chemistry 19(21): 6718-6723. Total synthesis of (+)-pleuromutilin. (PMID 23589420)