SmeABC

Accession ARO:3003050
DefinitionSmeABC is a multidrug resistance efflux pump that confers resistance to aminoglycosides, beta-lactams, and fluoroquinolones in Stenotrophomonas maltophilia
AMR Gene Familyresistance-nodulation-cell division (RND) antibiotic efflux pump
Drug Classaminoglycoside antibiotic, cephalosporin, cephamycin, penam
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification8 ontology terms | Show
Parent Term(s)5 ontology terms | Show
+ confers_resistance_to_drug_class aminoglycoside antibiotic [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class cephamycin [Drug Class]
+ resistance-nodulation-cell division (RND) antibiotic efflux pump [AMR Gene Family]
+ confers_resistance_to_drug_class penam [Drug Class]
Sub-Term(s)
4 ontology terms | Show
+ smeA part_of
+ smeB part_of
+ smeC part_of
+ smeRS regulates
Publications

Li XZ, et al. 2002. Antimicrob Agents Chemother 46(2): 333-343. SmeC, an outer membrane multidrug efflux protein of Stenotrophomonas maltophilia. (PMID 11796339)