Accession ARO:3003062
DefinitionykkCD is a multidrug efflux pump with two SMR-type protein subunits that confers resistance to cationic drugs, chloramphenicol, streptomycin and tetracycline.
AMR Gene Familysmall multidrug resistance (SMR) antibiotic efflux pump
Drug Classtetracycline antibiotic, phenicol antibiotic, aminoglycoside antibiotic
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification9 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ confers_resistance_to_antibiotic streptomycin [Antibiotic]
+ confers_resistance_to_antibiotic tetracycline [Antibiotic]
+ small multidrug resistance (SMR) antibiotic efflux pump [AMR Gene Family]
+ confers_resistance_to_antibiotic chloramphenicol [Antibiotic]
2 ontology terms | Show
+ ykkC part_of
+ ykkD part_of

Jack DL, et al. 2000. J Bacteriol 182(8): 2311-2313. A broad-specificity multidrug efflux pump requiring a pair of homologous SMR-type proteins. (PMID 10735877)