small multidrug resistance (SMR) antibiotic efflux pump [AMR Gene Family]

Accession ARO:0010003
Synonym(s)SMR type drug efflux
DefinitionDirected pumping of antibiotic out of a cell to confer resistance. Small multidrug resistance (SMR) proteins are a relatively small family of transporters, restricted to prokaryotic cells. They are also the smallest multidrug transporters, with only four transmembrane alpha-helices and no significant extramembrane domain.
Resistance Mechanismantibiotic efflux
Efflux Componentefflux pump complex or subunit conferring antibiotic resistance
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
4 ontology terms | Show
+ emrE
+ abeS
+ ykkCD
+ qacH
Publications

Bay DC, et al. 2008. Biochim Biophys Acta 1778(9): 1814-1838. Small multidrug resistance proteins: a multidrug transporter family that continues to grow. (PMID 17942072)