CGB beta-lactamase [AMR Gene Family]

Accession ARO:3004203
DefinitionCGB beta-lactamases are Class B beta-lactamases found in Chryseobacterium gleu that can hydrolyze penicillins; narrow- and expanded-spectrum cephalosporins; and carbapenems.
Drug Classpenam, carbapenem, cephalosporin
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ subclass B1 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class penam [Drug Class]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
1 ontology terms | Show

Bellais S, et al. 2002. Antimicrob Agents Chemother 46(9): 2791-2796. Genetic and biochemical characterization of CGB-1, an Ambler class B carbapenem-hydrolyzing beta-lactamase from Chryseobacterium gleum. (PMID 12183230)