EBR beta-lactamase [AMR Gene Family]

Accession ARO:3004204
DefinitionEBR beta-lactamases are Class B beta-lactamases first isolated from Empedobacter brevis and are able to hydrolyze penicillins, cephalosporins, and carbapenems.
Drug Classpenam, cephalosporin, carbapenem
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ subclass B1 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class penam [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
5 ontology terms | Show

Bellais S, et al. 2002. Antimicrob Agents Chemother 46(10): 3223-3227. EBR-1, a novel Ambler subclass B1 beta-lactamase from Empedobacter brevis. (PMID 12234848)