TUS beta-lactamase [AMR Gene Family]

Accession ARO:3004205
DefinitionTUS beta-lactamases are Class B beta-lactamases that can hydrolyze a variety of beta-lactams, such as cephems and carbapenems.
Drug Classcephalosporin, carbapenem, cephamycin
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ subclass B1 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class cephamycin [Drug Class]
1 ontology terms | Show

Mammeri H, et al. 2002. Antimicrob Agents Chemother 46(11): 3561-3567. Chromosome-encoded beta-lactamases TUS-1 and MUS-1 from Myroides odoratus and Myroides odoratimimus (formerly Flavobacterium odoratum), new members of the lineage of molecular subclass B1 metalloenzymes. (PMID 12384365)

Dharne MS, et al. 2008. Braz. J. Microbiol. 39(2):397-404 Antibacterial activities of multi drug resistant Myroides odoratimimus bacteria isolated from adult flesh flies (Diptera: sarcophagidae) are independent of metallo beta-lactamase gene. (PMID 24031236)