SMB beta-lactamase [AMR Gene Family]

Accession ARO:3004217
DefinitionSMB beta-lactamases are a subclass B3 beta-lactamases that hydrolyze a variety of beta-lactams, including penicillins, cephalosporins, and carbapenems.
Drug Classcarbapenem, penam, cephalosporin
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ subclass B3 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class penam [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
1 ontology terms | Show

Wachino J, et al. 2012. Acta Crystallogr Sect F Struct Biol Cryst Commun 68(PT 3): 343-346. Crystallization and preliminary X-ray analysis of the subclass B3 metallo-beta-lactamase SMB-1 that confers carbapenem resistance. (PMID 22442240)