Accession | ARO:3005020 |
Definition | The cfr(D) group are cfr(D) genes found in Enterococcus faecium that confer resistance to vancomycin, teicoplanin and linezolid. |
AMR Gene Family | Cfr 23S ribosomal RNA methyltransferase |
Drug Class | lincosamide antibiotic, oxazolidinone antibiotic, streptogramin antibiotic, phenicol antibiotic |
Resistance Mechanism | antibiotic target alteration |
Classification | 14 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + determinant of antibiotic resistance + antibiotic target alteration [Resistance Mechanism] + ribosomal alteration conferring antibiotic resistance + antibiotic target modifying enzyme + rRNA methyltransferase conferring antibiotic resistance + antibiotic molecule + 23S ribosomal RNA methyltransferase + lincosamide antibiotic [Drug Class] + oxazolidinone antibiotic [Drug Class] + streptogramin antibiotic [Drug Class] + S-adenosylmethionine (SAM) superfamily + phenicol antibiotic [Drug Class] |
Parent Term(s) | 1 ontology terms | Show + Cfr 23S ribosomal RNA methyltransferase [AMR Gene Family] |
Sub-Term(s) | 1 ontology terms | Show + cfr(D) |
Publications | Guerin F, et al. 2020. J. Antimicrob. Chemother. : Molecular and functional analysis of the novel cfr(D) linezolid resistance gene identified in Enterococcus faecium. (PMID 32277823) Stojković V, et al. 2019. Antimicrob. Agents Chemother. 64(1): cfr(B), cfr(C), and a New cfr-Like Gene, cfr(E), in Clostridium difficile Strains Recovered across Latin America. (PMID 31685464) |