ANT3310 [Adjuvant]

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Accession ARO:3007009
DefinitionAn experimental diazabicyclooctane beta-lactamase inhibitor that contains a fluorine atom in place of the carboxamide.
Classification5 ontology terms | Show
Parent Term(s)6 ontology terms | Show
+ diazabicyclooctane
+ is_small_molecule_inhibitor CTX-M-15
+ is_small_molecule_inhibitor KPC-2
+ is_small_molecule_inhibitor OXA-23
+ is_small_molecule_inhibitor OXA-48
+ is_small_molecule_inhibitor TEM-1

Davies DT, et al. 2020. J Med Chem 63(24):15802-15820 Discovery of ANT3310, a Novel Broad-Spectrum Serine β-Lactamase Inhibitor of the Diazabicyclooctane Class, Which Strongly Potentiates Meropenem Activity against Carbapenem-Resistant Enterobacterales and Acinetobacter baumannii. (PMID 33306385)