PAM beta-lactamase [AMR Gene Family]

Accession ARO:3007198
DefinitionA family of subclass B3 metallo-beta-lactamases discovered in Pseudomonas alcaligenes and found in other members of the Pseudomonas genus. PAM beta-lactamases hydrolyze cephalosporins and carbenems.
Drug Classcarbapenem, cephalosporin
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ subclass B3 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
3 ontology terms | Show

Suzuki M, et al. 2014. J Antimicrob Chemother 69(5):1430-2 A subclass B3 metallo-β-lactamase found in Pseudomonas alcaligenes. (PMID 24356301)

Yamada K, et al. 2021. J Glob Antimicrob Resist 24:395-397 Complete whole-genome sequence of the novel Pseudomonas species strain TUM18999, isolated from a patient with a burn wound in Japan. (PMID 33577996)