IMI beta-lactamase [AMR Gene Family]

Accession ARO:3000018
DefinitionIMI beta-lactamases are a group of TEM-1-like beta-lactamase that are known to hydrolyze imipenem. IMI beta-lactamases are inhibited by clavulanic acid and tazobactam.
Drug Classcarbapenem
Resistance Mechanismantibiotic inactivation
Classification11 ontology terms | Show
Parent Term(s)2 ontology terms | Show
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ class A beta-lactamase
Sub-Term(s)
9 ontology terms | Show
Publications

Rasmussen BA, et al. 1996. Antimicrob Agents Chemother 40(9): 2080-2086. Characterization of IMI-1 beta-lactamase, a class A carbapenem-hydrolyzing enzyme from Enterobacter cloacae. (PMID 8878585)