G418 [Antibiotic]

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Accession ARO:3000653
Synonym(s)geneticin
DefinitionA gentamicin class aminoglycoside antibiotic often used in mammalian cell culture work as a selectable marker for the neo cassette (APH3').
Drug Classaminoglycoside antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
Sub-Term(s)
9 ontology terms | Show
+ ANT(4') [AMR Gene Family] confers_resistance_to_antibiotic
+ APH(3') [AMR Gene Family] confers_resistance_to_antibiotic
+ armA confers_resistance_to_antibiotic
+ rmtA confers_resistance_to_antibiotic
+ rmtB confers_resistance_to_antibiotic
+ rmtC confers_resistance_to_antibiotic
+ sgm confers_resistance_to_antibiotic
+ Escherichia coli 16S rRNA (rrsB) mutation conferring resistance to G418 confers_resistance_to_antibiotic
+ antibiotic sensitive 16S rRNA targeted_by_antibiotic
Publications

Panchal CJ, et al. 1984. Appl Environ Microbiol 47(5): 1164-1166. Susceptibility of Saccharomyces spp. and Schwanniomyces spp. to the aminoglycoside antibiotic G418. (PMID 6378088)

Colbere-Garapin F, et al. 1985. Dev Biol Stand 59: 109-112. Stable HBV surface antigen expression by Vero cell clones after transfection. (PMID 4007271)