msrB

Accession ARO:3002818
Synonym(s)msr(B)
DefinitionMsrB is an ABC-F subfamily protein expressed to Staphylococcus species that confers resistance to erythromycin and streptogramin B antibiotics. It is associated with plasmid DNA.
AMR Gene FamilyABC-F ATP-binding cassette ribosomal protection protein
Drug Classtetracycline antibiotic, pleuromutilin antibiotic, streptogramin antibiotic, phenicol antibiotic, lincosamide antibiotic, macrolide antibiotic, oxazolidinone antibiotic
Resistance Mechanismantibiotic target protection
Classification14 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ confers_resistance_to_drug_class macrolide antibiotic [Drug Class]
+ confers_resistance_to_drug_class streptogramin antibiotic [Drug Class]
+ msr-type ABC-F protein
Publications

Milton ID, et al. 1992. FEMS Microbiol Lett 76(1-2): 141-147. Cloning and sequencing of a plasmid-mediated erythromycin resistance determinant from Staphylococcus xylosus. (PMID 1426997)

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