GIM beta-lactamase [AMR Gene Family]

Accession ARO:3003195
Synonym(s)blaGIM-1
DefinitionGIM beta-lactamase enzymes isolated from Pseudomonas aeruginosa, and found to confer broad-spectrum resistance to beta-lactam antibiotics.
Drug Classmonobactam, carbapenem, cephalosporin, cephamycin, penam, penem
Resistance Mechanismantibiotic inactivation
Classification13 ontology terms | Show
Parent Term(s)7 ontology terms | Show
+ confers_resistance_to_drug_class monobactam [Drug Class]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
+ confers_resistance_to_drug_class cephamycin [Drug Class]
+ confers_resistance_to_drug_class penam [Drug Class]
+ subclass B1 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class penem [Drug Class]
Sub-Term(s)
2 ontology terms | Show
Publications

Castanheira M, et al. 2004. Antimicrob Agents Chemother 48(12): 4654-4661. Molecular characterization of a beta-lactamase gene, blaGIM-1, encoding a new subclass of metallo-beta-lactamase. (PMID 15561840)