FEZ beta-lactamase [AMR Gene Family]

Accession ARO:3004211
DefinitionThe FEZ family of beta-lactamases are subclass B3 beta-lactamases that hydrolyze penicillins, cephalosporins, and carbapenems.
Drug Classpenam, carbapenem, cephalosporin
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ subclass B3 (metallo-) beta-lactamase
+ confers_resistance_to_drug_class penam [Drug Class]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class cephalosporin [Drug Class]
1 ontology terms | Show

Lienard BM, et al. 2008. Org Biomol Chem 6(13): 2282-2294. Structural basis for the broad-spectrum inhibition of metallo-beta-lactamases by thiols. (PMID 18563261)