Ontology | CARD's Antibiotic Resistance Ontology |
Accession | ARO:3004610 |
Definition | The cfr groups were determined by Candela et al (2017) by determining the phylogenetic relationship using the neighbour-joining method to compare the cfr-like proteins to cfr. |
AMR Gene Family | Cfr 23S ribosomal RNA methyltransferase |
Drug Class | phenicol antibiotic, oxazolidinone antibiotic, streptogramin antibiotic, lincosamide antibiotic |
Resistance Mechanism | antibiotic target alteration |
Classification | 14 ontology terms | Show + process or component of antibiotic biology or chemistry + mechanism of antibiotic resistance + determinant of antibiotic resistance + antibiotic target alteration [Resistance Mechanism] + antibiotic target modifying enzyme + ribosomal alteration conferring antibiotic resistance + rRNA methyltransferase conferring antibiotic resistance + 23S ribosomal RNA methyltransferase + antibiotic molecule + S-adenosylmethionine (SAM) superfamily + phenicol antibiotic [Drug Class] + oxazolidinone antibiotic [Drug Class] + streptogramin antibiotic [Drug Class] + lincosamide antibiotic [Drug Class] |
Parent Term(s) | 1 ontology terms | Show + Cfr 23S ribosomal RNA methyltransferase [AMR Gene Family] |
Sub-Term(s) | 1 ontology terms | Show + cfrC |
Publications | Candela T, et al. 2017. Int. J. Antimicrob. Agents 50(3):496-500 A cfr-Like Gene cfr(C) Conferring Linezolid Resistance is Common in Clostridium difficile. (PMID 28663118) |
Curator | Description | Most Recent Edit |
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