Accession ARO:3007384
DefinitionA family of aminoglycoside 3-N-acetyltransferase enzymes which inactivate gentamicin through enzymatic acetylation, thereby conferring resistance to these compounds.
AMR Gene FamilyAAC(3)
Drug Classaminoglycoside antibiotic
Resistance Mechanismantibiotic inactivation
Classification10 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ AAC(3) [AMR Gene Family]
4 ontology terms | Show

Shaw KJ, et al. 1993. Microbiol Rev 57(1): 138-163. Molecular genetics of aminoglycoside resistance genes and familial relationships of the aminoglycoside-modifying enzymes. (PMID 8385262)