ertapenem [Antibiotic]

Download Sequences

Accession ARO:0000070
DefinitionErtapenem is a carbapenem antibiotic and is highly resistant to beta-lactamases like other carbapenems. It inhibits bacterial cell wall synthesis.
Drug Classcarbapenem
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ carbapenem [Drug Class]
10 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ Klebsiella pneumoniae KpnGH-TolC confers_resistance_to_antibiotic
+ NDM-1 confers_resistance_to_antibiotic
+ NDM-5 confers_resistance_to_antibiotic
+ CTX-M-27 confers_resistance_to_antibiotic
+ CMY-2 confers_resistance_to_antibiotic
+ Klebsiella pneumoniae OmpK35 confers_resistance_to_antibiotic
+ VIM-63 confers_resistance_to_antibiotic
+ VCC-1 confers_resistance_to_antibiotic
+ FRI-11 confers_resistance_to_antibiotic

Shah PM and Isaacs RD. 2003. J Antimicrob Chemother 52(4): 538-542. Ertapenem, the first of a new group of carbapenems. (PMID 12951340)

Sakoulas G, et al. 2016. Antimicrob. Agents Chemother. : Cefazolin and Ertapenem: A Synergistic Combination Used to Clear Persistent Staphylococcus aureus Bacteremia. (PMID 27572414)