Xeruborbactam [Adjuvant]

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Accession ARO:3007048
DefinitionXeruborbactam is an experimental cyclic boronate ultrabroad-spectrum beta-lactamase inhibitor, with potent activity against both serine beta-lactamases and metallo-beta-lactamases.
Classification5 ontology terms | Show
Parent Term(s)8 ontology terms | Show
+ boronic acid beta-lactamase inhibitor
+ is_small_molecule_inhibitor CTX-M-14
+ is_small_molecule_inhibitor CTX-M-15
+ is_small_molecule_inhibitor KPC-2
+ is_small_molecule_inhibitor OXA-23
+ is_small_molecule_inhibitor OXA-48
+ is_small_molecule_inhibitor SHV-12
+ is_small_molecule_inhibitor TEM-10

Lomovskaya O, et al. 2022. Antimicrob Agents Chemother 66(2):e0216821 The Ultrabroad-Spectrum Beta-Lactamase Inhibitor QPX7728 Restores the Potency of Multiple Oral Beta-Lactam Antibiotics against Beta-Lactamase-Producing Strains of Resistant Enterobacterales. (PMID 34902261)