cefuroxime [Antibiotic]

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Accession ARO:0000063
Synonym(s)Cefuril Cefuroximum Biofuroksym Zinacef Sharox Cephuroxime Cefuroximo Cefuroxim CXM
DefinitionCefuroxime is a second-generation cephalosporin antibiotic with increased stability with beta-lactamases than first-generation cephalosporins. Cefuroxime is active against Gram-positive organisms but less active against methicillin-resistant strains.
Drug Classcephalosporin
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ cephalosporin [Drug Class]
11 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ CMY-136 confers_resistance_to_antibiotic
+ SCO-1 confers_resistance_to_antibiotic
+ LAP-1 confers_resistance_to_antibiotic
+ LAP-2 confers_resistance_to_antibiotic
+ MAB confers_resistance_to_antibiotic
+ Yrc-1 confers_resistance_to_antibiotic
+ Sed-1 confers_resistance_to_antibiotic
+ EBR-5 confers_resistance_to_antibiotic
+ CAE-1 confers_resistance_to_antibiotic
+ ACC-4 confers_resistance_to_antibiotic

Ryan DM, et al. 1976. Antimicrob Agents Chemother 9(3): 520-525. Cefuroxime, a new cephalosporin antibiotic: activity in vivo. (PMID 1259408)