pristinamycin IA [Antibiotic]

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Accession ARO:3000583
DefinitionPristinamycin IA is a type B streptogramin antibiotic produced by Streptomyces pristinaespiralis. It binds to the P site of the 50S subunit of the bacterial ribosome, preventing the extension of protein chains.
Drug Classstreptogramin antibiotic, streptogramin B antibiotic
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
28 ontology terms | Show
+ antibiotic sensitive peptidyl transferase (23S rRNA) targeted_by_antibiotic
+ ErmC confers_resistance_to_antibiotic
+ ErmE confers_resistance_to_antibiotic
+ ErmA confers_resistance_to_antibiotic
+ ErmB confers_resistance_to_antibiotic
+ Erm(37) confers_resistance_to_antibiotic
+ ErmD confers_resistance_to_antibiotic
+ ErmF confers_resistance_to_antibiotic
+ ErmG confers_resistance_to_antibiotic
+ ErmN confers_resistance_to_antibiotic
+ ErmQ confers_resistance_to_antibiotic
+ ErmR confers_resistance_to_antibiotic
+ ErmT confers_resistance_to_antibiotic
+ ErmX confers_resistance_to_antibiotic
+ Erm(33) confers_resistance_to_antibiotic
+ Erm(34) confers_resistance_to_antibiotic
+ Erm(38) confers_resistance_to_antibiotic
+ Erm(39) confers_resistance_to_antibiotic
+ Erm(41) confers_resistance_to_antibiotic
+ Erm(35) confers_resistance_to_antibiotic
+ Erm(36) confers_resistance_to_antibiotic
+ Streptococcus pneumoniae 23S rRNA mutation conferring resistance to macrolides and streptogramins antibiotics confers_resistance_to_antibiotic
+ vgbA confers_resistance_to_antibiotic
+ vgbB confers_resistance_to_antibiotic
+ vgbC confers_resistance_to_antibiotic
+ Erm(43) confers_resistance_to_antibiotic
+ Erm(48) confers_resistance_to_antibiotic
+ erm(45) confers_resistance_to_antibiotic