| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3000583 |
| Synonym(s) | Virginiamycin B |
| Definition | Pristinamycin IA is a type B streptogramin antibiotic produced by Streptomyces pristinaespiralis. It binds to the P site of the 50S subunit of the bacterial ribosome, preventing the extension of protein chains. |
| SMILES | CC[C@H]1NC(=O)[C@@H](NC(=O)c2ncccc2O)[C@@H](C)OC(=O)[C@H](c2ccccc2)NC(=O)[C@@H]2CC(=O)CCN2C(=O)[C@H](Cc2ccc(N(C)C)cc2)N(C)C(=O)[C@@H]2CCCN2C1=O |
| PubChem | 11136668 |
| ChEMBL | CHEMBL1256399 |
| ChEBI | 8417 |
| Drug Class | streptogramin antibiotic, streptogramin B antibiotic |
| Classification | 3 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + streptogramin B antibiotic [Drug Class] |
| Sub-Term(s) | 29 ontology terms | Show + antibiotic sensitive peptidyl transferase (23S rRNA) targeted_by_antibiotic + ErmC confers_resistance_to_antibiotic + ErmE confers_resistance_to_antibiotic + ErmA confers_resistance_to_antibiotic + ErmB confers_resistance_to_antibiotic + Erm(37) confers_resistance_to_antibiotic + ErmD confers_resistance_to_antibiotic + ErmF confers_resistance_to_antibiotic + ErmG confers_resistance_to_antibiotic + ErmN confers_resistance_to_antibiotic + ErmQ confers_resistance_to_antibiotic + ErmR confers_resistance_to_antibiotic + ErmT confers_resistance_to_antibiotic + ErmX confers_resistance_to_antibiotic + Erm(33) confers_resistance_to_antibiotic + Erm(34) confers_resistance_to_antibiotic + Erm(38) confers_resistance_to_antibiotic + Erm(39) confers_resistance_to_antibiotic + Erm(41) confers_resistance_to_antibiotic + Erm(35) confers_resistance_to_antibiotic + Erm(36) confers_resistance_to_antibiotic + Streptococcus pneumoniae 23S rRNA mutation conferring resistance to macrolides and streptogramins antibiotics confers_resistance_to_antibiotic + vgbA confers_resistance_to_antibiotic + vgbB confers_resistance_to_antibiotic + vgbC confers_resistance_to_antibiotic + Erm(43) confers_resistance_to_antibiotic + Erm(48) confers_resistance_to_antibiotic + erm(45) confers_resistance_to_antibiotic + erm(56) confers_resistance_to_antibiotic |
| Curator | Description | Most Recent Edit |
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