meropenem [Antibiotic]

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Accession ARO:0000073
Synonym(s)Meronem Merrem Meropen meropenem Meropenemum Meropenem anhydrous
DefinitionMeropenem is an ultra-broad spectrum injectable antibiotic used to treat a wide variety of infections, including meningitis and pneumonia. It is a beta-lactam and belongs to the subgroup of carbapenem, similar to imipenem and ertapenem.
Drug Classcarbapenem
Classification3 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ carbapenem [Drug Class]
Sub-Term(s)
12 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ CAM-1 confers_resistance_to_antibiotic
+ MexAB-OprM confers_resistance_to_antibiotic
+ NDM-1 confers_resistance_to_antibiotic
+ Acinetobacter baumannii AbuO confers_resistance_to_antibiotic
+ MexAB-OprM with prematurely terminated MexR conferring resistance to meropenem and ciprofloxacin confers_resistance_to_antibiotic
+ MexAB-OprM with MexR mutations confers resistance to multiple antibiotics confers_resistance_to_antibiotic
+ OXA-2 confers_resistance_to_antibiotic
+ MexXY-OprM confers_resistance_to_antibiotic
+ MexXY-OprA confers_resistance_to_antibiotic
+ MexAB-OprM with NalC mutations conferring resistance to aztreonam confers_resistance_to_antibiotic
+ Vibrio cholerae varG confers_resistance_to_antibiotic
Publications

Baldwin CM, et al. 2008. Drugs 68(6): 803-838. Meropenem: a review of its use in the treatment of serious bacterial infections. (PMID 18416587)