LEN beta-lactamase [AMR Gene Family]

Accession ARO:3000097
DefinitionLEN beta-lactamases are chromosomal class A beta-lactamases that confer resistance to ampicillin, amoxicillin, carbenicillin, and ticarcillin but not to extended-spectrum beta-lactams.
Drug Classpenam, penem
Resistance Mechanismantibiotic inactivation
Classification12 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ confers_resistance_to_drug_class penam [Drug Class]
+ SHV-LEN beta-lactamase
+ confers_resistance_to_drug_class penem [Drug Class]
Sub-Term(s)
29 ontology terms | Show
Publications

Haeggman S, et al. 2004. Antimicrob Agents Chemother 48(7): 2400-2408. Diversity and evolution of the class A chromosomal beta-lactamase gene in Klebsiella pneumoniae. (PMID 15215087)