OXA-213-like beta-lactamase [AMR Gene Family]

Accession ARO:3007706
DefinitionOXA-213-like enzymes have been identified to be intrinsic to A. calcoaceticus and have been subsequently detected in A. pittii. Phylogenetic analysis of OXA-213-like proteins identified two distinct subgroups within the OXA family. The first group was linked to A. pittii and the second group to A. calcoaceticus. The carbapenemase activity of these OXAs may be related to the species-dependent effect.
AMR Gene FamilyOXA beta-lactamase
Drug Classpenam, carbapenem
Resistance Mechanismantibiotic inactivation
Classification13 ontology terms | Show
Parent Term(s)3 ontology terms | Show
+ OXA beta-lactamase [AMR Gene Family]
+ confers_resistance_to_drug_class carbapenem [Drug Class]
+ confers_resistance_to_drug_class penam [Drug Class]
66 ontology terms | Show

Evans BA, et al. 2014. Clin Microbiol Rev 27(2): 241-263. OXA beta-Lactamases. (PMID 24696435)