basRS

Accession ARO:3003579
Synonym(s)pmrAB
DefinitionBasRS is a two-component regulatory system. BasR is phosphorylated by BasS at high[Fe3+] levels. The BasRS system regulates the expression of pmrE, pmrF and pmrC, leading to antibiotic resistance
AMR Gene Familypmr phosphoethanolamine transferase
Drug Classpeptide antibiotic
Resistance Mechanismantibiotic target alteration
Classification13 ontology terms | Show
Parent Term(s)4 ontology terms | Show
+ determinant of polymyxin resistance
+ regulates arnA
+ regulates ugd
+ regulates PmrF
Sub-Term(s)
3 ontology terms | Show
+ phoPQ regulates
+ basS part_of
+ basR part_of
Publications

Lee JY, et al. 2014. Diagn Microbiol Infect Dis 78(3): 271-276. Mutations and expression of PmrAB and PhoPQ related with colistin resistance in Pseudomonas aeruginosa clinical isolates. (PMID 24412662)