vaborbactam [Adjuvant]

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Ontology CARD's Antibiotic Resistance Ontology
Accession ARO:3004380
DefinitionAntibiotic adjuvant and serine beta-lactamase inhibitor, often paired with meropenem for clinical use.
SMILESO=C(O)C[C@@H]1CC[C@H](NC(=O)Cc2cccs2)B(O)O1
PubChem56649692
ChEMBLCHEMBL3317857
Classification5 ontology terms | Show
Parent Term(s)13 ontology terms | Show
+ is_small_molecule_inhibitor_of SHV-5
+ is_small_molecule_inhibitor_of SHV-18
+ is_small_molecule_inhibitor_of CTX-M-3
+ is_small_molecule_inhibitor_of CTX-M-14
+ is_small_molecule_inhibitor_of CTX-M-15
+ is_small_molecule_inhibitor_of CMY-2
+ is_small_molecule_inhibitor_of DHA-1
+ is_small_molecule_inhibitor_of MIR-1
+ is_small_molecule_inhibitor_of KPC-2
+ is_small_molecule_inhibitor_of KPC-3
+ is_small_molecule_inhibitor_of SME-2
+ is_small_molecule_inhibitor_of NmcA
+ boronic acid beta-lactamase inhibitor
Sub-Term(s)
1 ontology terms | Show
+ meropenem-vaborbactam [Antibiotic+Adjuvant] has_part
Publications

Bush K, et al. 2018. ACS Infect Dis 4(2):84-87 Game Changers: New β-Lactamase Inhibitor Combinations Targeting Antibiotic Resistance in Gram-Negative Bacteria. (PMID 29232103)

Curator Acknowledgements
Curator Description Most Recent Edit