cefazolin [Antibiotic]

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Accession ARO:0000058
Synonym(s)Cephamezine Cephazolidin Cephazoline Elzogram Cefazolinum Cephazolin Cefazolina CFZ Cefamezin Cefazoline
DefinitionCefazolin (INN), also known as cefazoline or cephazolin, is a first generation cephalosporin antibiotic. It is administered parenterally, and is active against a broad spectrum of bacteria.
Drug Classcephalosporin
Classification4 ontology terms | Show
Parent Term(s)1 ontology terms | Show
+ cephalosporin [Drug Class]
14 ontology terms | Show
+ beta-lactam sensitive penicillin-binding protein targeted_by_antibiotic
+ porin OmpC confers_resistance_to_antibiotic
+ NmcA confers_resistance_to_antibiotic
+ CMY-2 confers_resistance_to_antibiotic
+ CTX-M-3 confers_resistance_to_antibiotic
+ CTX-M-27 confers_resistance_to_antibiotic
+ TEM-1 confers_resistance_to_antibiotic
+ CTX-M-15 confers_resistance_to_antibiotic
+ PDC-3 confers_resistance_to_antibiotic
+ PDC-5 confers_resistance_to_antibiotic
+ PRC-1 confers_resistance_to_antibiotic
+ LAQ-1 confers_resistance_to_antibiotic
+ CAE-1 confers_resistance_to_antibiotic
+ PSZ-1 confers_resistance_to_antibiotic

Reller LB, et al. 1973. Antimicrob Agents Chemother 3(4): 488-497. Evaluation of cefazolin, a new cephalosporin antibiotic. (PMID 4790605)

Sakoulas G, et al. 2016. Antimicrob. Agents Chemother. : Cefazolin and Ertapenem: A Synergistic Combination Used to Clear Persistent Staphylococcus aureus Bacteremia. (PMID 27572414)