isepamicin [Antibiotic]

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Accession ARO:3000652
Synonym(s)isepamicine isepamicinum
DefinitionA semi-synthetic derivative of gentamicin B (hydroxyamino propionyl genamicin B). It is modified to combat microbial inactivation and has a slightly larger spectrum of activity compared to other aminoglycosides, including Ser marcescens, Enterobacteria, and K pneumoniae.
Drug Classaminoglycoside antibiotic
Classification2 ontology terms | Show
Parent Term(s)1 ontology terms | Show
17 ontology terms | Show
+ ANT(4') [AMR Gene Family] confers_resistance_to_antibiotic
+ AAC(6')-Iag confers_resistance_to_antibiotic
+ APH(2'') [AMR Gene Family] confers_resistance_to_antibiotic
+ armA confers_resistance_to_antibiotic
+ rmtA confers_resistance_to_antibiotic
+ rmtB confers_resistance_to_antibiotic
+ rmtC confers_resistance_to_antibiotic
+ sgm confers_resistance_to_antibiotic
+ APH(3')-VIa confers_resistance_to_antibiotic
+ APH(3')-VIb confers_resistance_to_antibiotic
+ APH(3')-VI confers_resistance_to_antibiotic
+ AAC(6')-29b confers_resistance_to_antibiotic
+ AAC(6')-29a confers_resistance_to_antibiotic
+ AAC(6')-31 confers_resistance_to_antibiotic
+ AAC(6')-Iae confers_resistance_to_antibiotic
+ AAC(6')-Iai confers_resistance_to_antibiotic
+ antibiotic sensitive 16S rRNA targeted_by_antibiotic

Barr WH, et al. 1995. J Chemother 7(SUPPL 2): 53-61. Pharmacokinetics of isepamicin. (PMID 8622111)