| Ontology | CARD's Antibiotic Resistance Ontology |
| Accession | ARO:3000652 |
| Synonym(s) | isepamicine isepamicinum |
| Definition | A semi-synthetic derivative of gentamicin B (hydroxyamino propionyl genamicin B). It is modified to combat microbial inactivation and has a slightly larger spectrum of activity compared to other aminoglycosides, including Ser marcescens, Enterobacteria, and K pneumoniae. |
| SMILES | CN[C@@H]1[C@@H](O)[C@@H](O[C@@H]2[C@@H](O)[C@H](O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3O)[C@@H](N)C[C@H]2NC(=O)[C@@H](O)CN)OC[C@]1(C)O |
| PubChem | 3037209 |
| ChEMBL | CHEMBL272080 |
| Drug Class | aminoglycoside antibiotic |
| Classification | 2 ontology terms | Show |
| Parent Term(s) | 1 ontology terms | Show + aminoglycoside antibiotic [Drug Class] |
| Sub-Term(s) | 16 ontology terms | Show + antibiotic sensitive 16S rRNA targeted_by_antibiotic + armA confers_resistance_to_antibiotic + rmtA confers_resistance_to_antibiotic + rmtB confers_resistance_to_antibiotic + rmtC confers_resistance_to_antibiotic + sgm confers_resistance_to_antibiotic + APH(3')-VIa confers_resistance_to_antibiotic + APH(3')-VIb confers_resistance_to_antibiotic + AAC(6')-29b confers_resistance_to_antibiotic + AAC(6')-29a confers_resistance_to_antibiotic + AAC(6')-31 confers_resistance_to_antibiotic + ANT(4')-Ia confers_resistance_to_antibiotic + ANT(4')-Ib confers_resistance_to_antibiotic + ANT(4')-IIa confers_resistance_to_antibiotic + ANT(4')-IIb confers_resistance_to_antibiotic + APH(3')-IIIa confers_resistance_to_antibiotic |
| Publications | Barr WH, et al. 1995. J Chemother 7(SUPPL 2): 53-61. Pharmacokinetics of isepamicin. (PMID 8622111) |
| Curator | Description | Most Recent Edit |
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